Protein Name syndecan 2
Organism Homo sapiens
Gene ID 6383
Gene Symbol


UniProt P34741 (SDC2_HUMAN), E9PBI9 (E9PBI9_HUMAN), A0A024R9D1 (A0A024R9D1_HUMAN)
Relationships Total Number of functionally related compound(s) : 149
Total Number of Articles : 194

syndecan 2

Gene Summary

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008]

  • syndecan-2
  • cell surface-associated heparan sulfate proteoglycan 1
  • fibroglycan
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