Protein Name OS9 endoplasmic reticulum lectin
Organism Homo sapiens
Gene ID 10956
Gene Symbol

OS9

UniProt Q13438 (OS9_HUMAN)
Relationships Total Number of functionally related compound(s) : 32
Total Number of Articles : 26
Description

OS9 endoplasmic reticulum lectin

Gene Summary

This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

synonyms
  • protein OS-9
  • amplified in osteosarcoma 9
  • endoplasmic reticulum lectin 2
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Properties