| Protein Name | ER degradation enhancing alpha-mannosidase like protein 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 9695 |
| Gene Symbol | EDEM1 |
| UniProt | Q92611 (EDEM1_HUMAN), A0A024R2D5 (A0A024R2D5_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
31
Total Number of Articles : 32 |
Description |
ER degradation enhancing alpha-mannosidase like protein 1 |
| Gene Summary |
Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity and misfolded protein binding activity. Involved in mannose trimming involved in glycoprotein ERAD pathway; positive regulation of retrograde protein transport, ER to cytosol; and protein targeting to ER. Located in aggresome and endoplasmic reticulum quality control compartment. [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |