Protein Name MAD2 mitotic arrest deficient-like 2
Organism Mus musculus
Gene ID 71890
Gene Symbol

Mad2l2

UniProt Q9D752 (MD2L2_MOUSE), A2A7G7 (A2A7G7_MOUSE)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 10
Description

MAD2 mitotic arrest deficient-like 2

Gene Summary

Predicted to enable JUN kinase binding activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and transcription corepressor activity. Predicted to be involved in several processes, including DNA repair; regulation of epithelial to mesenchymal transition; and regulation of primary metabolic process. Predicted to be located in nucleoplasm and spindle. Predicted to be part of anaphase-promoting complex and zeta DNA polymerase complex. Predicted to be active in nucleus. Is expressed in several structures, including brain; ganglia; gonad; hemolymphoid system gland; and intestine. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group V. Orthologous to human MAD2L2 (mitotic arrest deficient 2 like 2). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • mitotic spindle assembly checkpoint protein MAD2B
  • MAD2-like protein 2
  • mitotic arrest deficient 2-like protein 2
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Properties