Protein Name | mitogen-activated protein kinase HOG1 |
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Organism | Saccharomyces cerevisiae S288C |
Gene ID | 850803 |
Gene Symbol | HOG1 |
UniProt | P32485 (HOG1_YEAST) |
Relationships |
Total Number of functionally related compound(s) :
99
Total Number of Articles : 176 |
Description |
mitogen-activated protein kinase HOG1 |
Gene Summary |
Enables MAP kinase activity; calmodulin binding activity; and chromatin binding activity. Involved in several processes, including cellular response to osmotic stress; positive regulation of transcription by RNA polymerase II; and regulation of cell cycle process. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in several diseases, including abdominal aortic aneurysm; carcinoma (multiple); chronic mucocutaneous candidiasis; colorectal cancer (multiple); and intestinal benign neoplasm (multiple). Orthologous to several human genes including MAPK12 (mitogen-activated protein kinase 12) and MAPK13 (mitogen-activated protein kinase 13). [provided by Alliance of Genome Resources, Jul 2025] |
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Properties | |