Protein Name mitogen-activated protein kinase HOG1
Organism Saccharomyces cerevisiae S288C
Gene ID 850803
Gene Symbol

HOG1

UniProt P32485 (HOG1_YEAST)
Relationships Total Number of functionally related compound(s) : 99
Total Number of Articles : 176
Description

mitogen-activated protein kinase HOG1

Gene Summary

Enables MAP kinase activity; calmodulin binding activity; and chromatin binding activity. Involved in several processes, including cellular response to osmotic stress; positive regulation of transcription by RNA polymerase II; and regulation of cell cycle process. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in several diseases, including abdominal aortic aneurysm; carcinoma (multiple); chronic mucocutaneous candidiasis; colorectal cancer (multiple); and intestinal benign neoplasm (multiple). Orthologous to several human genes including MAPK12 (mitogen-activated protein kinase 12) and MAPK13 (mitogen-activated protein kinase 13). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • mitogen-activated protein kinase HOG1
  • YLR113W
  • SSK3
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Properties