Protein Name glutathione reductase
Organism Mus musculus
Gene ID 14782
Gene Symbol

Gsr

UniProt P47791 (GSHR_MOUSE)
Relationships Total Number of functionally related compound(s) : 282
Total Number of Articles : 345
Description

glutathione reductase

Gene Summary

Enables glutathione-disulfide reductase (NADPH) activity. Predicted to be involved in several processes, including cell redox homeostasis; cellular response to oxidative stress; and glutathione metabolic process. Located in external side of plasma membrane. Is expressed in brain ventricular layer; gut; lung; metanephros; and retina. Human ortholog(s) of this gene implicated in cataract and macular degeneration. Orthologous to human GSR (glutathione-disulfide reductase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • glutathione reductase, mitochondrial
  • GR
  • GRase
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Properties