| Protein Name | protein kinase C, iota |
|---|---|
| Organism | Mus musculus |
| Gene ID | 18759 |
| Gene Symbol | Prkci |
| UniProt | Q62074 (KPCI_MOUSE), Q5DTK3 (Q5DTK3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
41
Total Number of Articles : 36 |
Description |
protein kinase C, iota |
| Gene Summary |
Enables diacylglycerol-dependent, calcium-independent serine/threonine kinase activity. Involved in cellular response to insulin stimulus; positive regulation of D-glucose import; and positive regulation of protein localization to plasma membrane. Acts upstream of or within actin filament organization; establishment of apical/basal cell polarity; and eye photoreceptor cell development. Located in several cellular components, including Schmidt-Lanterman incisure; apical plasma membrane; and brush border. Is expressed in several structures, including alimentary system; brain; genitourinary system; lung; and sensory organ. Used to study abdominal obesity-metabolic syndrome; obesity; and type 2 diabetes mellitus. Orthologous to human PRKCI (protein kinase C iota). [provided by Alliance of Genome Resources, Jul 2025] |
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