Protein Name proviral integration site 2
Organism Mus musculus
Gene ID 18715
Gene Symbol

Pim2

UniProt Q62070 (PIM2_MOUSE), Q8R1Z0 (Q8R1Z0_MOUSE)
Relationships Total Number of functionally related compound(s) : 21
Total Number of Articles : 15
Description

proviral integration site 2

Gene Summary

Enables protein serine/threonine kinase activity. Involved in several processes, including positive regulation of canonical NF-kappaB signal transduction; positive regulation of metabolic process; and protein stabilization. Acts upstream of or within apoptotic mitochondrial changes; negative regulation of apoptotic process; and positive regulation of macroautophagy. Predicted to be active in cytoplasm. Is expressed in several structures, including exocrine gland; genitourinary system; hemolymphoid system gland; nervous system; and nose. Orthologous to human PIM2 (Pim-2 proto-oncogene, serine/threonine kinase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • serine/threonine-protein kinase pim-2
  • DXCch3
  • Pim-2
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Properties