| Protein Name | allograft inflammatory factor 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 11629 |
| Gene Symbol | Aif1 |
| UniProt | O70200 (AIF1_MOUSE), Q4FJL9 (Q4FJL9_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
65
Total Number of Articles : 64 |
Description |
allograft inflammatory factor 1 |
| Gene Summary |
Enables actin filament binding activity and calcium ion binding activity. Involved in several processes, including Rac protein signal transduction; actin filament organization; and ruffle assembly. Acts upstream of or within actin filament bundle assembly. Located in several cellular components, including actin filament; phagocytic cup; and ruffle membrane. Is expressed in several structures, including adrenal cortex; brain; embryo mesenchyme; retina; and spinal cord. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human AIF1 (allograft inflammatory factor 1). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |