Protein Name malate dehydrogenase 2
Organism Homo sapiens
Gene ID 4191
Gene Symbol

MDH2

UniProt P40926 (MDHM_HUMAN), G3XAL0 (G3XAL0_HUMAN), A0A024R4K3 (A0A024R4K3_HUMAN), B3KTM1 (B3KTM1_HUMAN)
Relationships Total Number of functionally related compound(s) : 104
Total Number of Articles : 68
Description

malate dehydrogenase 2

Gene Summary

Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

synonyms
  • malate dehydrogenase, mitochondrial
  • malate dehydrogenase 2, NAD (mitochondrial)
  • testicular tissue protein Li 120
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Properties