Protein Name | malate dehydrogenase 2 |
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Organism | Homo sapiens |
Gene ID | 4191 |
Gene Symbol | MDH2 |
UniProt | P40926 (MDHM_HUMAN), G3XAL0 (G3XAL0_HUMAN), A0A024R4K3 (A0A024R4K3_HUMAN), B3KTM1 (B3KTM1_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
104
Total Number of Articles : 68 |
Description |
malate dehydrogenase 2 |
Gene Summary |
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] |
synonyms |
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Properties | |