| Protein Name | solute carrier family 22 (organic cation transporter), member 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 20518 |
| Gene Symbol | Slc22a2 |
| UniProt | O70577 (S22A2_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
37
Total Number of Articles : 35 |
Description |
solute carrier family 22 (organic cation transporter), member 2 |
| Gene Summary |
Enables several functions, including pyrimidine nucleoside transmembrane transporter activity; toxin transmembrane transporter activity; and xenobiotic transmembrane transporter activity. Involved in cellular detoxification and xenobiotic transport. Acts upstream of or within monoatomic cation transport. Located in apical plasma membrane. Is expressed in several structures, including metanephros; nasal cavity mucosa; nervous system; placenta; and ureter. Human ortholog(s) of this gene implicated in acute kidney failure. Orthologous to human SLC22A2 (solute carrier family 22 member 2). [provided by Alliance of Genome Resources, Jul 2025] |
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