Protein Name | Rab7 |
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Organism | Drosophila melanogaster |
Gene ID | 42841 |
Gene Symbol | Rab7 |
UniProt | O76742 (O76742_DROME) |
Relationships |
Total Number of functionally related compound(s) :
3
Total Number of Articles : 3 |
Description |
Rab7 |
Gene Summary |
Predicted to enable GTPase activity. Involved in several processes, including endocytosis; endosomal transport; and vesicle fusion. Located in cell cortex and late endosome membrane. Is active in phagocytic vesicle. Is expressed in several structures, including brain; glial cell; imaginal disc; mushroom body; and synaptic neuropil domain. Used to study Charcot-Marie-Tooth disease type 2. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2B. Orthologous to human RAB7A (RAB7A, member RAS oncogene family). [provided by Alliance of Genome Resources, Jul 2025] |
synonyms |
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Properties | |