Protein Name activity dependent neuroprotector homeobox
Organism Homo sapiens
Gene ID 23394
Gene Symbol

ADNP

UniProt Q9H2P0 (ADNP_HUMAN), Q6DHZ8 (Q6DHZ8_HUMAN)
Relationships Total Number of functionally related compound(s) : 33
Total Number of Articles : 39
Description

activity dependent neuroprotector homeobox

Gene Summary

Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

synonyms
  • activity-dependent neuroprotector homeobox protein
  • ADNP homeobox 1
  • activity-dependent neuroprotective protein
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Properties