| Protein Name | senataxin |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 23064 |
| Gene Symbol | SETX |
| UniProt | Q7Z333 (SETX_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
19
Total Number of Articles : 10 |
Description |
senataxin |
| Gene Summary |
This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4). [provided by RefSeq, Jul 2008] |
| synonyms |
|
| Properties | |