Protein Name glycerol phosphate dehydrogenase 2, mitochondrial
Organism Mus musculus
Gene ID 14571
Gene Symbol

Gpd2

UniProt Q64521 (GPDM_MOUSE)
Relationships Total Number of functionally related compound(s) : 96
Total Number of Articles : 84
Description

glycerol phosphate dehydrogenase 2, mitochondrial

Gene Summary

Enables glycerol-3-phosphate dehydrogenase (quinone) activity. Involved in glycerol-3-phosphate shuttle. Acts upstream of or within camera-type eye development; gluconeogenesis; and glycerol-3-phosphate metabolic process. Located in mitochondrion. Is active in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study citrullinemia. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human GPD2 (glycerol-3-phosphate dehydrogenase 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • glycerol-3-phosphate dehydrogenase, mitochondrial
  • FAD-linked glycerol-3-phosphate dehydrogenase
  • glycerol phosphate dehydrogenase 1, mitochondrial
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Properties