Protein Name peroxiredoxin HYR1
Organism Saccharomyces cerevisiae S288C
Gene ID 854855
Gene Symbol

HYR1

UniProt P40581 (GPX3_YEAST)
Relationships Total Number of functionally related compound(s) : 42
Total Number of Articles : 40
Description

peroxiredoxin HYR1

Gene Summary

Enables glutathione peroxidase activity and phospholipid-hydroperoxide glutathione peroxidase activity. Involved in cellular response to oxidative stress. Located in mitochondrial intermembrane space and peroxisomal matrix. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia Sedaghatian type and type 2 diabetes mellitus. Orthologous to several human genes including GPX4 (glutathione peroxidase 4). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • peroxiredoxin HYR1
  • YIR037W
  • GPX3
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Properties