Protein Name actinin alpha 2
Organism Rattus norvegicus
Gene ID 291245
Gene Symbol

Actn2

UniProt D3ZCV0 (D3ZCV0_RAT)
Relationships Total Number of functionally related compound(s) : 9
Total Number of Articles : 8
Description

actinin alpha 2

Gene Summary

A structural constituent of postsynaptic actin cytoskeleton. Predicted to be involved in several processes, including focal adhesion assembly; regulation of monoatomic ion transport; and striated muscle cell development. Located in cortical actin cytoskeleton. Is active in glutamatergic synapse; postsynaptic actin cytoskeleton; and postsynaptic density. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular cardiomyopathy; congenital myopathy 8; and dilated cardiomyopathy 1AA. Orthologous to human ACTN2 (actinin alpha 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • alpha-actinin-2
Click to show/hide the synonyms
Properties