Protein Name | actinin alpha 2 |
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Organism | Rattus norvegicus |
Gene ID | 291245 |
Gene Symbol | Actn2 |
UniProt | D3ZCV0 (D3ZCV0_RAT) |
Relationships |
Total Number of functionally related compound(s) :
9
Total Number of Articles : 8 |
Description |
actinin alpha 2 |
Gene Summary |
A structural constituent of postsynaptic actin cytoskeleton. Predicted to be involved in several processes, including focal adhesion assembly; regulation of monoatomic ion transport; and striated muscle cell development. Located in cortical actin cytoskeleton. Is active in glutamatergic synapse; postsynaptic actin cytoskeleton; and postsynaptic density. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular cardiomyopathy; congenital myopathy 8; and dilated cardiomyopathy 1AA. Orthologous to human ACTN2 (actinin alpha 2). [provided by Alliance of Genome Resources, Jul 2025] |
synonyms |
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Properties | |