| Protein Name | transaldolase 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6888 |
| Gene Symbol | TALDO1 |
| UniProt | P37837 (TALDO_HUMAN), A0A140VK56 (A0A140VK56_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
159
Total Number of Articles : 140 |
Description |
transaldolase 1 |
| Gene Summary |
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008] |
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| Properties | |