Protein Name | NLR family CARD domain containing 3 |
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Organism | Homo sapiens |
Gene ID | 197358 |
Gene Symbol | NLRC3 |
UniProt | Q7RTR2 (NLRC3_HUMAN), C3VPR7 (C3VPR7_HUMAN), Q8NF06 (Q8NF06_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
8
Total Number of Articles : 8 |
Description |
NLR family CARD domain containing 3 |
Gene Summary |
This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
synonyms |
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Properties | |