Protein Name NLR family CARD domain containing 3
Organism Homo sapiens
Gene ID 197358
Gene Symbol

NLRC3

UniProt Q7RTR2 (NLRC3_HUMAN), C3VPR7 (C3VPR7_HUMAN), Q8NF06 (Q8NF06_HUMAN)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 8
Description

NLR family CARD domain containing 3

Gene Summary

This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

synonyms
  • NLR family CARD domain-containing protein 3
  • CARD15-like protein
  • NACHT, LRR and CARD domains-containing protein 3
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Properties