Protein Name prostaglandin I2 synthase
Organism Rattus norvegicus
Gene ID 25527
Gene Symbol


UniProt Q62969 (PTGIS_RAT)
Relationships Total Number of functionally related compound(s) : 56
Total Number of Articles : 52

prostaglandin I2 synthase

Gene Summary

Enables prostaglandin-I synthase activity. Involved in prostaglandin biosynthetic process and response to hypoxia. Located in extracellular space. Used to study brain ischemia and pulmonary hypertension. Human ortholog(s) of this gene implicated in essential hypertension and hypertension. Orthologous to human PTGIS (prostaglandin I2 synthase). [provided by Alliance of Genome Resources, Apr 2022]

  • prostacyclin synthase
  • hydroperoxy icosatetraenoate dehydratase
  • prostaglandin I2 (prostacyclin) synthase
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