Protein Name glutathione S-transferase mu 1
Organism Rattus norvegicus
Gene ID 24423
Gene Symbol

Gstm1

UniProt P04905 (GSTM1_RAT)
Relationships Total Number of functionally related compound(s) : 76
Total Number of Articles : 48
Description

glutathione S-transferase mu 1

Gene Summary

Enables several functions, including glutathione binding activity; glutathione transferase activity; and nickel cation binding activity. Involved in several processes, including glutathione metabolic process; response to ethanol; and response to lead ion. Located in cytosol and extracellular region. Part of protein-containing complex. Used to study cholestasis. Biomarker of hypertension and liver cirrhosis. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to human GSTM1 (glutathione S-transferase mu 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • glutathione S-transferase Mu 1
  • GST 3-3
  • GST Yb1
Click to show/hide the synonyms
Properties