Protein Name unc-5 netrin receptor C
Organism Homo sapiens
Gene ID 8633
Gene Symbol

UNC5C

UniProt O95185 (UNC5C_HUMAN), A8K385 (A8K385_HUMAN)
Relationships Total Number of functionally related compound(s) : 9
Total Number of Articles : 7
Description

unc-5 netrin receptor C

Gene Summary

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008]

synonyms
  • netrin receptor UNC5C
  • protein unc-5 homolog 3
  • protein unc-5 homolog C
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Properties