| Protein Name | unc-5 netrin receptor B |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 219699 |
| Gene Symbol | UNC5B |
| UniProt | Q8IZJ1 (UNC5B_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
22
Total Number of Articles : 18 |
Description |
unc-5 netrin receptor B |
| Gene Summary |
This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011] |
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| Properties | |