Protein Name tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Organism Mus musculus
Gene ID 21951
Gene Symbol

Tnks

UniProt Q6PFX9 (TNKS1_MOUSE)
Relationships Total Number of functionally related compound(s) : 16
Total Number of Articles : 11
Description

tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase

Gene Summary

Predicted to enable several functions, including histone binding activity; pentosyltransferase activity; and telomerase inhibitor activity. Predicted to be involved in several processes, including positive regulation of canonical Wnt signaling pathway; post-translational protein modification; and regulation of chromosome organization. Predicted to act upstream of or within peptidyl-serine phosphorylation and peptidyl-threonine phosphorylation. Located in cytosol. Is expressed in several structures, including blastocyst; central nervous system; early embryo; neural retina; and oocyte. Orthologous to human TNKS (tankyrase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • poly [ADP-ribose] polymerase tankyrase-1
  • ADP-ribosyltransferase diphtheria toxin-like 5
  • TRF1-interacting ankyrin-related ADP-ribose polymerase 1
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Properties