Protein Name solute carrier family 4 member 4
Organism Rattus norvegicus
Gene ID 84484
Gene Symbol

Slc4a4

UniProt Q9JI66 (S4A4_RAT)
Relationships Total Number of functionally related compound(s) : 36
Total Number of Articles : 34
Description

solute carrier family 4 member 4

Gene Summary

Predicted to enable identical protein binding activity and sodium:bicarbonate symporter activity. Predicted to be involved in bicarbonate transport; regulation of intracellular pH; and sodium ion export across plasma membrane. Located in membrane. Used to study nephrogenic diabetes insipidus. Biomarker of hypertension. Human ortholog(s) of this gene implicated in renal tubular acidosis. Orthologous to human SLC4A4 (solute carrier family 4 member 4). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • electrogenic sodium bicarbonate cotransporter 1
  • NBC-like protein
  • Na(+)/HCO3(-) cotransporter
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Properties