| Protein Name | three prime repair exonuclease 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 11277 |
| Gene Symbol | TREX1 |
| UniProt | Q9NSU2 (TREX1_HUMAN), Q5TZT0 (Q5TZT0_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
56
Total Number of Articles : 41 |
Description |
three prime repair exonuclease 1 |
| Gene Summary |
This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012] |
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| Properties | |