Protein Name Ras association (RalGDS/AF-6) domain family member 1
Organism Mus musculus
Gene ID 56289
Gene Symbol

Rassf1

UniProt Q99MK9 (RASF1_MOUSE), A9YZW8 (A9YZW8_MOUSE), Q3UIV8 (Q3UIV8_MOUSE)
Relationships Total Number of functionally related compound(s) : 28
Total Number of Articles : 20
Description

Ras association (RalGDS/AF-6) domain family member 1

Gene Summary

Enables small GTPase binding activity. Predicted to be involved in several processes, including Ras protein signal transduction; positive regulation of protein ubiquitination; and protein stabilization. Predicted to act upstream of with a negative effect on regulation of cell cycle G1/S phase transition. Predicted to be located in cytoplasm and microtubule cytoskeleton. Predicted to be active in microtubule cytoskeleton and nucleus. Is expressed in liver; metanephros; and neural retina. Human ortholog(s) of this gene implicated in breast cancer; carcinoma (multiple); reproductive organ cancer (multiple); and urinary bladder cancer. Orthologous to human RASSF1 (Ras association domain family member 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • ras association domain-containing protein 1
  • 123F protein
  • RASSF1A tumor suppressor
Click to show/hide the synonyms
Properties