Protein Name 3-hydroxy-3-methylglutaryl-CoA synthase 1
Organism Rattus norvegicus
Gene ID 29637
Gene Symbol

Hmgcs1

UniProt P17425 (HMCS1_RAT)
Relationships Total Number of functionally related compound(s) : 7
Total Number of Articles : 7
Description

3-hydroxy-3-methylglutaryl-CoA synthase 1

Gene Summary

Enables hydroxymethylglutaryl-CoA synthase activity; isomerase activity; and organic acid binding activity. Involved in several processes, including cellular response to cholesterol; cellular response to follicle-stimulating hormone stimulus; and response to vitamin E. Predicted to be located in cytoplasm. Biomarker of obesity. Orthologous to human HMGCS1 (3-hydroxy-3-methylglutaryl-CoA synthase 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • hydroxymethylglutaryl-CoA synthase, cytoplasmic
  • 3-hydroxy-3-methylglutaryl coenzyme A synthase
  • 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
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Properties