Protein Name early growth response 2b
Organism Danio rerio
Gene ID 30190
Gene Symbol

egr2b

UniProt Q66HY5 (Q66HY5_DANRE)
Relationships Total Number of functionally related compound(s) : 2
Total Number of Articles : 3
Description

early growth response 2b

Gene Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within embryonic organ development and nervous system development. Predicted to be located in nucleus. Is expressed in several structures, including nervous system; neural crest; neural keel; neural plate; and neural rod. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1D; Charcot-Marie-Tooth disease type 3; Charcot-Marie-Tooth disease type 4E; and motor peripheral neuropathy. Orthologous to human EGR2 (early growth response 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • early growth response protein 2b
  • EGR-2b
  • krox-20
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Properties