Protein Name DNA topoisomerase II binding protein 1 L homeolog
Organism Xenopus laevis
Gene ID 398573
Gene Symbol

topbp1.L

UniProt Q800K6 (TOB1A_XENLA), A0A1L8FWJ6 (A0A1L8FWJ6_XENLA)
Relationships Total Number of functionally related compound(s) : 7
Total Number of Articles : 6
Description

DNA topoisomerase II binding protein 1 L homeolog

Gene Summary

Enables chromatin binding activity and kinase binding activity. Acts upstream of or within several processes, including DNA metabolic process; DNA replication checkpoint signaling; and positive regulation of protein phosphorylation. Located in chromatin and nucleus. Orthologous to human TOPBP1 (DNA topoisomerase II binding protein 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • DNA topoisomerase II binding protein 1 L homeolog
  • Cut5-related protein
  • DNA topoisomerase 2-binding protein 1-A
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Properties