| Protein Name | tet methylcytosine dioxygenase 2 |
|---|---|
| Organism | Danio rerio |
| Gene ID | 101887161 |
| Gene Symbol | tet2 |
| UniProt | E7F958 (E7F958_DANRE) |
| Relationships |
Total Number of functionally related compound(s) :
3
Total Number of Articles : 6 |
Description |
tet methylcytosine dioxygenase 2 |
| Gene Summary |
Enables DNA 5-methylcytosine dioxygenase activity and broad specificity oxidative DNA demethylase activity. Involved in regulation of gene expression. Acts upstream of or within cell surface receptor signaling pathway; endothelial to hematopoietic transition; and hemopoiesis. Predicted to be located in chromosome. Predicted to be active in nucleus. Is expressed in several structures, including cardiovascular system; eye; hematopoietic system; liver; and pleuroperitoneal region. Used to study myelodysplastic syndrome. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); hematologic cancer (multiple); lung non-small cell carcinoma; and primary immunodeficiency disease. Orthologous to human TET2 (tet methylcytosine dioxygenase 2). [provided by Alliance of Genome Resources, Jul 2025] |
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