Protein Name ATP binding cassette subfamily B member 1A
Organism Rattus norvegicus
Gene ID 170913
Gene Symbol

Abcb1a

UniProt Q9JK64 (Q9JK64_RAT)
Relationships Total Number of functionally related compound(s) : 112
Total Number of Articles : 101
Description

ATP binding cassette subfamily B member 1A

Gene Summary

Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and ATPase-coupled intramembrane lipid transporter activity. Involved in several processes, including cellular hyperosmotic salinity response; cellular response to L-glutamate; and cellular response to borneol. Located in brush border membrane. Biomarker of brain disease (multiple); end stage renal disease; human immunodeficiency virus infectious disease; liver disease (multiple); and obstructive sleep apnea. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); drug dependence (multiple); human immunodeficiency virus infectious disease (multiple); inflammatory bowel disease (multiple); and leukemia (multiple). Orthologous to human ABCB1 (ATP binding cassette subfamily B member 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • ATP binding cassette subfamily B member 1A
  • ATP binding cassette subfamily B member 1
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1
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Properties