| Protein Name | activating transcription factor 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 11909 |
| Gene Symbol | Atf2 |
| UniProt | P16951 (ATF2_MOUSE), Q543G2 (Q543G2_MOUSE), Q640L6 (Q640L6_MOUSE), Q8CBR9 (Q8CBR9_MOUSE), Q68FE3 (Q68FE3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
95
Total Number of Articles : 103 |
Description |
activating transcription factor 2 |
| Gene Summary |
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; cAMP response element binding activity; and protein dimerization activity. Involved in several processes, including growth plate cartilage development; hindbrain development; and intracellular signal transduction. Acts upstream of or within with a positive effect on cellular response to leucine starvation and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including adipose tissue development; brown fat cell proliferation; and positive regulation of transforming growth factor beta2 production. Located in membrane; nucleus; and site of double-strand break. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and limb. Used to study meconium aspiration syndrome and osteochondrodysplasia. Orthologous to human ATF2 (activating transcription factor 2). [provided by Alliance of Genome Resources, Jun 2025] |
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