| Protein Name | GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 852815 |
| Gene Symbol | ALG2 |
| UniProt | P43636 (ALG2_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
32
Total Number of Articles : 15 |
Description |
GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase |
| Gene Summary |
Enables GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity and initiation-specific glycolipid 1,6-alpha-mannosyltransferase activity. Involved in dolichol-linked oligosaccharide biosynthetic process. Located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ii and congenital myasthenic syndrome 14. Orthologous to human ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |