| Protein Name | jagged 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 16450 |
| Gene Symbol | Jag2 |
| UniProt | Q9QYE5 (JAG2_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
10
Total Number of Articles : 9 |
Description |
jagged 2 |
| Gene Summary |
Enables Notch binding activity. Involved in auditory receptor cell fate commitment; gamma-delta T cell differentiation; and positive regulation of Notch signaling pathway. Acts upstream of or within several processes, including epithelial cell apoptotic process involved in palatal shelf morphogenesis; odontogenesis of dentin-containing tooth; and respiratory system process. Located in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and surface ectoderm. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy. Orthologous to human JAG2 (jagged canonical Notch ligand 2). [provided by Alliance of Genome Resources, Jun 2025] |
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