| Protein Name | dopamine receptor D4 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 13491 |
| Gene Symbol | Drd4 |
| UniProt | P51436 (DRD4_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
44
Total Number of Articles : 43 |
Description |
dopamine receptor D4 |
| Gene Summary |
Enables dopamine neurotransmitter receptor activity, coupled via Gi/Go. Involved in regulation of circadian rhythm and regulation of postsynaptic neurotransmitter receptor internalization. Acts upstream of or within several processes, including adenylate cyclase-inhibiting dopamine receptor signaling pathway; behavioral response to cocaine; and inhibitory postsynaptic potential. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; hemolymphoid system gland; integumental system; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including Gilles de la Tourette syndrome; antisocial personality disorder; attention deficit hyperactivity disorder; conduct disorder; and dyslexia. Orthologous to human DRD4 (dopamine receptor D4). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |