| Protein Name | tenascin C |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 116640 |
| Gene Symbol | Tnc |
| UniProt | B2LYI9 (B2LYI9_RAT), A0A0G2K1L0 (A0A0G2K1L0_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
95
Total Number of Articles : 88 |
Description |
tenascin C |
| Gene Summary |
Predicted to enable integrin binding activity and syndecan binding activity. Involved in several processes, including bud outgrowth involved in lung branching; cellular response to prostaglandin D stimulus; and cellular response to vitamin D. Is active in extracellular matrix of synaptic cleft and glutamatergic synapse. Used to study pulmonary hypertension. Biomarker of cholangiocarcinoma; high grade glioma; myocardial infarction; polycystic kidney disease; and pulmonary hypertension. Human ortholog(s) of this gene implicated in allergic conjunctivitis; asthma; and autosomal dominant nonsyndromic deafness 56. Orthologous to human TNC (tenascin C). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |