| Protein Name | carbonic anhydrase 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 12349 |
| Gene Symbol | Car2 |
| UniProt | P00920 (CAH2_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
327
Total Number of Articles : 361 |
Description |
carbonic anhydrase 2 |
| Gene Summary |
Enables carbonate dehydratase activity. Involved in positive regulation of dipeptide transmembrane transport and regulation of intracellular pH. Acts upstream of or within several processes, including positive regulation of GABAergic synaptic transmission; positive regulation of cellular pH reduction; and regulation of chloride transport. Located in cytosol and myelin sheath. Is expressed in several structures, including alimentary system; brain; heart; metanephros; and sensory organ. Used to study autosomal recessive osteopetrosis 3. Human ortholog(s) of this gene implicated in alcoholic pancreatitis; autoimmune disease (multiple); osteopetrosis (multiple); and viral hepatitis. Orthologous to human CA2 (carbonic anhydrase 2). [provided by Alliance of Genome Resources, Jun 2025] |
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