Protein Name | Abdominal B |
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Organism | Drosophila melanogaster |
Gene ID | 47763 |
Gene Symbol | Abd-B |
UniProt | P09087 (ABDB_DROME), A4V304 (A4V304_DROME), A0A0B4KGT1 (A0A0B4KGT1_DROME), A0A126GUV9 (A0A126GUV9_DROME), A0A126GUV3 (A0A126GUV3_DROME) |
Relationships |
Total Number of functionally related compound(s) :
8
Total Number of Articles : 8 |
Description |
Abdominal B |
Gene Summary |
Enables DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including genital disc development; male pigmentation; and reproductive structure development. Located in nucleus and polytene chromosome band. Is expressed in several structures, including adult posterior abdominal ganglion neurons; anterior-posterior subdivision of organism; epithelium; genital disc; and somatic trunk mesoderm derivative. Human ortholog(s) of this gene implicated in congenital vertical talus and radioulnar synostosis. Orthologous to several human genes including HOXA10 (homeobox A10); HOXA11 (homeobox A11); and HOXC10 (homeobox C10). [provided by Alliance of Genome Resources, Jul 2025] |
synonyms |
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Properties | |