Protein Name potassium two pore domain channel subfamily K member 3
Organism Rattus norvegicus
Gene ID 29553
Gene Symbol

Kcnk3

UniProt O54912 (KCNK3_RAT)
Relationships Total Number of functionally related compound(s) : 15
Total Number of Articles : 13
Description

potassium two pore domain channel subfamily K member 3

Gene Summary

Enables open rectifier potassium channel activity and protein heterodimerization activity. Involved in several processes, including cellular response to zinc ion; positive regulation of voltage-gated potassium channel activity; and regulation of resting membrane potential. Predicted to be located in membrane. Predicted to be active in plasma membrane. Used to study pulmonary hypertension and pulmonary venoocclusive disease. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in primary pulmonary hypertension. Orthologous to human KCNK3 (potassium two pore domain channel subfamily K member 3). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • potassium channel subfamily K member 3
  • TWIK-related acid-sensitive K(+) channel 1
  • TWIK-related acid-sensitive K+ channel
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Properties