CPRiL

Hspb8

heat shock protein 8

Predicted to enable protein homodimerization activity. Predicted to be involved in cellular response to unfolded protein and positive regulation of aggrephagy. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of protein folding chaperone complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study autosomal dominant distal hereditary motor neuronopathy 2. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2L; autosomal dominant distal hereditary motor neuronopathy 2; and myofibrillar myopathy 13 with rimmed vacuoles. Orthologous to human HSPB8 (heat shock protein family B (small) member 8). [provided by Alliance of Genome Resources, Jul 2025]

• heat shock protein beta-8
• alpha-crystallin C chain
• crystallin, alpha C
heat shock 27kDa protein 8
heat shock protein 20-like protein
small stress protein-like protein HSP22
Cryac
D5Ucla4
E2IG1
H11
H11K
HSP20-like
HSP22