| Protein Name | roundabout guidance receptor 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 19876 |
| Gene Symbol | Robo1 |
| UniProt | O89026 (ROBO1_MOUSE), G5E843 (G5E843_MOUSE), Q3UXH3 (Q3UXH3_MOUSE), Q3UQ03 (Q3UQ03_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
18
Total Number of Articles : 16 |
Description |
roundabout guidance receptor 1 |
| Gene Summary |
Predicted to enable LRR domain binding activity; axon guidance receptor activity; and identical protein binding activity. Involved in several processes, including circulatory system development; neuron development; and regulation of gene expression. Acts upstream of or within several processes, including axon guidance; heart development; and mammary duct terminal end bud growth. Located in axolemma. Is expressed in several structures, including autopod; central nervous system; genitourinary system; jaw; and sensory organ. Used to study cystic kidney disease and lung cancer. Human ortholog(s) of this gene implicated in autosomal recessive congenital nystagmus; combined or isolated pituitary hormone deficiency 8; congenital nystagmus; multiple myeloma; and plasmacytoma. Orthologous to human ROBO1 (roundabout guidance receptor 1). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |