| Protein Name | activin A receptor type 1C |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 130399 |
| Gene Symbol | ACVR1C |
| UniProt | Q8NER5 (ACV1C_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
20
Total Number of Articles : 20 |
Description |
activin A receptor type 1C |
| Gene Summary |
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008] |
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| Properties | |