Protein Name biglycan
Organism Homo sapiens
Gene ID 633
Gene Symbol


UniProt P21810 (PGS1_HUMAN), B4DNL4 (B4DNL4_HUMAN)
Relationships Total Number of functionally related compound(s) : 173
Total Number of Articles : 183


Gene Summary

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015]

  • biglycan
  • bone/cartilage proteoglycan-I
  • dermatan sulphate proteoglycan I
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