Protein Name sterol O-acyltransferase 1
Organism Homo sapiens
Gene ID 6646
Gene Symbol


UniProt P35610 (SOAT1_HUMAN)
Relationships Total Number of functionally related compound(s) : 256
Total Number of Articles : 278

sterol O-acyltransferase 1

Gene Summary

The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]

  • sterol O-acyltransferase 1
  • acyl-coenzyme A:cholesterol acyltransferase 1
  • sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
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