| Protein Name | sterol O-acyltransferase 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6646 |
| Gene Symbol | SOAT1 |
| UniProt | P35610 (SOAT1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
256
Total Number of Articles : 278 |
Description |
sterol O-acyltransferase 1 |
| Gene Summary |
The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011] |
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