| Protein Name | gremlin 2, DAN family BMP antagonist |
|---|---|
| Organism | Mus musculus |
| Gene ID | 23893 |
| Gene Symbol | Grem2 |
| UniProt | O88273 (GREM2_MOUSE), Q3TST1 (Q3TST1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
9
Total Number of Articles : 7 |
Description |
gremlin 2, DAN family BMP antagonist |
| Gene Summary |
Enables BMP binding activity; heparin binding activity; and identical protein binding activity. Involved in several processes, including determination of dorsal identity; embryonic body morphogenesis; and regulation of signal transduction. Located in extracellular space. Is expressed in several structures, including central nervous system; chondrocranium; gut; integument; and lung. Human ortholog(s) of this gene implicated in tooth agenesis. Orthologous to human GREM2 (gremlin 2, DAN family BMP antagonist). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |