CPRiL

Hspa8

heat shock protein family A (Hsp70) member 8

Enables several functions, including A1 adenosine receptor binding activity; ATP hydrolysis activity; and adenyl ribonucleotide binding activity. Involved in several processes, including brain development; intracellular protein transport; and protein-containing complex disassembly. Acts upstream of or within protein-containing complex disassembly. Located in several cellular components, including dendrite; polymeric cytoskeletal fiber; and vacuole. Part of protein-containing complex. Is active in several cellular components, including glutamatergic synapse; glycinergic synapse; and postsynaptic density. Biomarker of Parkinson's disease; acute kidney failure; brain ischemia (multiple); disease of metabolism; and graft-versus-host disease. Human ortholog(s) of this gene implicated in Parkinson's disease and renal hypertension. Orthologous to human HSPA8 (heat shock protein family A (Hsp70) member 8). [provided by Alliance of Genome Resources, Jun 2025]

• heat shock cognate 71 kDa protein
• Heat shock cognate protein 70
• heat shock 70kD protein 8
heat shock 70kDa protein 8
heat shock protein 8
heat shock protein A8
Hsc70