Protein Name UFM1 specific ligase 1
Organism Homo sapiens
Gene ID 23376
Gene Symbol

UFL1

UniProt O94874 (UFL1_HUMAN)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 6
Description

UFM1 specific ligase 1

Gene Summary

Enables UFM1 ligase activity and protein kinase binding activity. Involved in several processes, including positive regulation of reticulophagy; regulation of intracellular signal transduction; and regulation of primary metabolic process. Acts upstream of or within several processes, including positive regulation of cell population proliferation; regulation of proteasomal ubiquitin-dependent protein catabolic process; and response to endoplasmic reticulum stress. Located in cytoplasm; nucleus; and site of double-strand break. Part of protein-containing complex. Is active in endoplasmic reticulum membrane and mitochondrial outer membrane. [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • E3 UFM1-protein ligase 1
  • E3 UFM1-protein transferase 1
  • LZAP-binding protein
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Properties