Protein Name p21 (RAC1) activated kinase 1
Organism Rattus norvegicus
Gene ID 29431
Gene Symbol


UniProt P35465 (PAK1_RAT)
Relationships Total Number of functionally related compound(s) : 46
Total Number of Articles : 33

p21 (RAC1) activated kinase 1

Gene Summary

Enables protein kinase binding activity and protein serine/threonine kinase activity. Involved in several processes, including negative regulation of cell growth involved in cardiac muscle cell development; nervous system development; and positive regulation of cell migration. Located in several cellular components, including Z disc; intercalated disc; and ruffle. Biomarker of brain ischemia. Human ortholog(s) of this gene implicated in breast cancer; renal cell carcinoma; and schizophrenia. Orthologous to human PAK1 (p21 (RAC1) activated kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

  • serine/threonine-protein kinase PAK 1
  • PAK-1
  • alpha-PAK
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