| Protein Name | cytochrome P450, family 27, subfamily a, polypeptide 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 301517 |
| Gene Symbol | Cyp27a1 |
| UniProt | P17178 (CP27A_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
44
Total Number of Articles : 54 |
Description |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
| Gene Summary |
Enables Hsp70 protein binding activity; cholesterol 26-hydroxylase activity; and vitamin D3 25-hydroxylase activity. Involved in cholesterol metabolic process. Located in mitochondrial inner membrane. Biomarker of extrahepatic cholestasis. Human ortholog(s) of this gene implicated in cerebrotendinous xanthomatosis. Orthologous to human CYP27A1 (cytochrome P450 family 27 subfamily A member 1). [provided by Alliance of Genome Resources, Jun 2025] |
| synonyms |
|
| Properties | |